Reena Gupta

Professor

Dr. Reena Gupta is a Professor of Medicine at the University of California, San Francisco in the Division of General Internal Medicine at San Francisco General Hospital. She is a public health leader and primary care physician focused on delivery of high quality health care services for non-communicable diseases (NCDs) at the primary care level in low- and middle-income countries.

Dr. Gupta is Chief Medical Officer, Performance Improvement for Cardiovascular Health at Resolve to Save Lives, a global organization that partners with ministries of health, WHO, and local partners to implement patient-centered hypertension and diabetes programs in primary care settings across 40 countries. These programs currently provide treatment to over 40 million people in more than 220,000 health facilities. In this role, she provides strategic and technical guidance to improve the quality of health services for the control of hypertension, diabetes, and dyslipidemia.

She serves on several international advisory groups including the World Health Organization Technical Advisory Group for Diabetes and the World Health Organization Dyslipidemia Guideline Development Group.

Dr Gupta received her medical degree from Harvard Medical School, completed residency in internal medicine at UCSF, and is a practicing physician at San Francisco General Hospital.
Education
Residency, - School of Medicine - Primary Care, University of California, San Francisco
Custom Faculty Group
Core
Publications

  1. Quiambao A, Malekpour MR, Golestani A, Heidari-Foroozan M, Ghamari SH, Abbasi-Kangevari M, Anderson BO, Barango P, Fidarova E, Hemmingsen B, Ilbawi A, Khan T, Sequeria RO, Roglic G, Rylance S, Roitberg F, Riley L, Slama S, Bhatti L, Cowan M, Rarau P, Savin S, Farzadfar F, Agboyibor KM, Aggarwal AN, Akala O, Angkurawaranon C, Chu HA, Anjana RM, Antini C, Aziz Z, Barkley S, Basit A, Basu P, Majano SB, Bennoor K, Brettler JW, Cabioglu N, Caixeta R, Campbell N, Chavez C, Choudhury SR, Corbex MA, Cruz A, Daceney N, Dalal S, Danaei G, Dangou JM, De Groote W, Diallo CB, Dille I, Domingo RE, Dorji G, Duncan BB, Egere U, El Berri H, El Sony A, Eltigani M, Farrington J, Fouad H, Friedrich P, Fuentes-Alabi S, Gamarra A, Gregg E, Gupta R, Gupta S, Jia W, Jiagge E, Jousilahti P, Kesavan R, Kumar S, Laatikainen T, Larijani B, Losada ML, Le Thi TL, Levitt N, Luciani S, Maza M, Mikkelsen B, Mohammad Y, Moran A, Motlagh A, Mulupi S, Murillo RH, Mutebi M, Nantanda R, Nyirenda M, O'Connor P, Ojji D, Omoro GE, Ondarsuhu D, Ordunez P, Sidi Mohamed MO, Owolabi M, Rahimi K, Rakovac I, Raposo JF, Rosende A, Rowley J, Sankaranarayanan R, Smelov V, Tiko J, Tonelli M, Tsoyi E, Tuttle T, Varghese C, Vásquez L, Viswanathan K, Xu H, Yip CH. World health Organization's guidance for tracking non-communicable diseases towards sustainable development goals 3.4: an initiative for facility-based monitoring. EClinicalMedicine 2025. PMID: 40678696


  2. Moran AE, Aimiosior O, Gupta R, Pathni A, Sahoo SK, Dessie G, Osi K, Zhang X, Banigbe B, Garg R, Frieden TR. Integrated Antihypertensive and Statin Treatment Protocols for Cardiovascular Disease Prevention in Low- and Middle-Income Countries. Global heart 2024. PMID: 39677503


  3. Jubayer S, Akhtar J, Abrar AK, Sayem MNN, Islam S, Amin KE, Nahid MF, Bhuiyan MR, Al Mamun MA, Alim A, Amin MR, Burka D, Gupta P, Zhao D, Matsushita K, Moran AE, Choudhury SR, Gupta R. Text messaging to improve retention in hypertension care in Bangladesh. Journal of human hypertension 2024. PMID: 39182005


  4. Abrar A, Hu X, Akhtar J, Jubayer S, Noor Nabi Sayem M, Sultana S, Al Mamun MA, Bhuiyan MR, Malik F, Amin MR, Alim A, Gupta R, Zhao D, Farrell M, Banigbe B, Matsushita K, Burka D, Appel L, Moran AE, Choudhury SR. Evaluation of the World Health Organization-HEARTS hypertension control package in Bangladesh: a quasi-experimental trial. Heart (British Cardiac Society) 2024. PMID: 39019496


  5. Staatz C, Loosier PS, Hsu R, Fiscus M, Gupta R, Sabin ER, Vohra D, Matulewicz H, Taylor MM, Caruso EC, DeLuca N, Moonan PK, Oeltmann JE, Thorpe P. Experience of Public Health Departments in Implementation of COVID-19 Case Investigation and Contact Tracing Programs. Public health reports (Washington, D.C. : 1974) 2024. PMID: 38779998


  6. Albitres-Flores L, Perez-Leon S, Bernabe-Ortiz A, Tenorio-Mucha J, Cardenas MK, Vetter B, Safary E, Gamboa R, Cordova V, Gupta R, Moran A, Beran D, Lazo-Porras M. Co-creation process of an intervention to implement a multiparameter point-of-care testing device in a primary healthcare setting for non-communicable diseases in Peru. BMC health services research 2024. PMID: 38553724


  7. Margiana R, Gupta R, Al-Jewari WM, Hjazi A, Alsaab HO, Mustafa YF, Singh R, Thaibt R, Alkhayyat S, Ibrahim AJ. Evaluation of telomere length, reactive oxygen species, and apoptosis in spermatozoa of patients with oligospermia. Cell biochemistry and function 2024. PMID: 38379260


  8. Ouyang L, Xia W, Al-Alwany AA, Gupta R, Sapaev I, Almalki SG, Almawash S, Ziyad RA, Alawadi AH, Alsalamy A. Ischemic Stroke and Autophagy: The Roles of Long Non-Coding RNAs. Current neuropharmacology 2024. PMID: 39021183


  9. Al-Hawary SIS, Ruzibakieva M, Gupta R, Malviya J, Toama MA, Hjazi A, Alkhayyat MRR, Alsaab HO, Hadi A, Alwaily ER. Detailed role of microRNA-mediated regulation of PI3K/AKT axis in human tumors. Cell biochemistry and function 2023. PMID: 38102946


  10. Zamanian MY, Ivraghi MS, Gupta R, Prasad KDV, Alsaab HO, Hussien BM, Ahmed H, Ramadan MF, Golmohammadi M, Nikbakht N, Oz T, Kujawska M. miR-221 and Parkinson's disease: A biomarker with therapeutic potential. The European journal of neuroscience 2023. PMID: 38043936


  11. Ivraghi MS, Zamanian MY, Gupta R, Achmad H, Alsaab HO, Hjazi A, Romero-Parra RM, Alwaily ER, Hussien BM, Hakimizadeh E. Neuroprotective effects of gemfibrozil in neurological disorders: Focus on inflammation and molecular mechanisms. CNS neuroscience & therapeutics 2023. PMID: 37904726


  12. Moran AE, Gupta R, Global Hearts Initiative Collaborators. Implementation of Global Hearts Hypertension Control Programs in 32 Low- and Middle-Income Countries: JACC International. Journal of the American College of Cardiology 2023. PMID: 37734459


  13. Al-Hawary SIS, Alsalamy A, Gupta R, Alsaab HO, Hjazi A, Edilboyev U, Ramadan MF, Hussien BM, Ahmed M, Hosseini-Fard SR. VAV3 in human cancers: Mechanism and clinical implication. Pathology, research and practice 2023. PMID: 37467637


  14. Jubayer S, Hasan MM, Luna M, Al Mamun MA, Bhuiyan MR, Sayem NN, Amin MR, Farrell M, Moran AE, Gupta R, Choudhury SR. Availability of Hypertension and Diabetes Mellitus Care Services at Subdistrict Level in Bangladesh. WHO South-East Asia journal of public health 2023. PMID: 38848529


  15. Gupta R, Kadhim MM, Turki Jalil A, Qasim Alasheqi M, Alsaikhan F, Khalimovna Mukhamedova N, Alexis Ramírez-Coronel A, Hassan Jawhar Z, Ramaiah P, Najafi M. The interactions of docetaxel with tumor microenvironment. International immunopharmacology 2023. PMID: 37126985


  16. Tenorio-Mucha J, Busta-Flores P, Lazo-Porras M, Vetter B, Safary E, Moran AE, Gupta R, Bernabé-Ortiz A. Facilitators and barriers of the implementation of point-of-care devices for cardiometabolic diseases: a scoping review. BMC health services research 2023. PMID: 37118750


  17. Chen A, Ayub MH, Mishuris RG, Rodriguez JA, Gwynn K, Lo MC, Noronha C, Henry TL, Jones D, Lee WW, Varma M, Cuevas E, Onumah C, Gupta R, Goodson J, Lu AD, Syed Q, Suen LW, Heiman E, Salhi BA, Khoong EC, Schmidt S. Telehealth Policy, Practice, and Education: a Position Statement of the Society of General Internal Medicine. Journal of general internal medicine 2023. PMID: 37095331


  18. Gupta GR, Grown C, Fewer S, Gupta R, Nowrojee S. Beyond gender mainstreaming: transforming humanitarian action, organizations and culture. Journal of international humanitarian action 2023. PMID: 37151809


  19. Gupta R, Kadhim MM, Turki Jalil A, Obayes AM, Aminov Z, Alsaikhan F, Ramírez-Coronel AA, Ramaiah P, Tayyib NA, Luo X. Multifaceted role of NF-κB in hepatocellular carcinoma therapy: Molecular landscape, therapeutic compounds and nanomaterial approaches. Environmental research 2023. PMID: 36966991


  20. Kapoor B, Gulati M, Gupta R, Singla RK. Microbiota dysbiosis and myasthenia gravis: Do all roads lead to Rome? Autoimmunity reviews 2023. PMID: 36918089


  21. Jing HH, Bardakci F, Akgöl S, Kusat K, Adnan M, Alam MJ, Gupta R, Sahreen S, Chen Y, Gopinath SCB, Sasidharan S. Green Carbon Dots: Synthesis, Characterization, Properties and Biomedical Applications. Journal of functional biomaterials 2023. PMID: 36662074


  22. Burka D, Gupta R, Moran AE, Cohn J, Choudhury SR, Cheadle T, Mullick R, Frieden TR. Keep it simple: designing a user-centred digital information system to support chronic disease management in low/middle-income countries. BMJ health & care informatics 2023. PMID: 36639189


  23. Alameri AA, Ghanni MU, Ali A, Singh M, Al-Gazally ME, Almulla AF, Alexis Ramírez-Coronel A, Mustafa YF, Gupta R, Obaid RF, Gabr GA, Farhood B. The Effects of Curcumin on Astrocytes in Common Neurodegenerative Conditions. Mini reviews in medicinal chemistry 2023. PMID: 37132107


  24. Latacela GA, Ramaiah P, Patra I, Jalil AT, Gupta R, Madaminov FA, Shaker Shafik S, Al-Gazally ME, Ansari MJ, Kandeel M, Mustafa YF, Farhood B. The Radioprotective Potentials of Silymarin/Silibinin Against Radiotherapy- Induced Toxicities: A Systematic Review of Clinical and Experimental Studies. Current medicinal chemistry 2023. PMID: 36424777


  25. Kapoor B, Gulati M, Rani P, Kochhar RS, Atanasov AG, Gupta R, Sharma D, Kapoor D. Lycopene: Sojourn from kitchen to an effective therapy in Alzheimer's disease. BioFactors (Oxford, England) 2022. PMID: 36318372


  26. Muzammil K, Solanki R, Alkaim AF, Romero Parra RM, Lafta HA, Jalil AT, Gupta R, Hammid AT, Mustafa YF. A novel approach based on the ultrasonic-assisted microwave method for the efficient synthesis of Sc-MOF@SiO2 core/shell nanostructures for H2S gas adsorption: A controllable systematic study for a green future. Frontiers in chemistry 2022. PMID: 36300018


  27. Gupta R, Rahi Alhachami F, Khalid I, Majdi HS, Nisar N, Mohamed Hasan Y, Sivaraman R, Romero Parra RM, Al Mashhadani ZI, Fakri Mustafa Y. Recent Progress in Aptamer-Functionalized Metal-Organic Frameworks-Based Optical and Electrochemical Sensors for Detection of Mycotoxins. Critical reviews in analytical chemistry 2022. PMID: 36197710


  28. Rohmah MK, Salahdin OD, Gupta R, Muzammil K, Qasim MT, Al-Qaim ZH, Abbas NF, Jawad MA, Yasin G, Mustafa YF, Heidary A, Abarghouei S. Modulatory role of dietary curcumin and resveratrol on growth performance, serum immunity responses, mucus enzymes activity, antioxidant capacity and serum and mucus biochemicals in the common carp, Cyprinus carpio exposed to abamectin. Fish & shellfish immunology 2022. PMID: 36007834


  29. Ratna R, Tibrewal S, Gour A, Gupta R, Mathur U, Vanita V. A rare case of congenital aniridia with an unusual run-on mutation in PAX6 gene. Indian journal of ophthalmology 2022. PMID: 35791194


  30. Rani P, Kapoor B, Gulati M, Atanasov AG, Alzahrani Q, Gupta R. Antimicrobial peptides: A plausible approach for COVID-19 treatment. Expert opinion on drug discovery 2022. PMID: 35255763


  31. Kaur R, Rani P, Atanasov AG, Alzahrani Q, Gupta R, Kapoor B, Gulati M, Chawla P. Discovery and Development of Antibacterial Agents: Fortuitous and Designed. Mini reviews in medicinal chemistry 2022. PMID: 34939541


  32. Schmidt S, Gupta R, Bracey J, Volerman A, Henry T, Jackson C, Levine D, Jones D, Richter JM, Schmidt J, Rotenstein L, Berger Z, Peairs K, Singh H, Schwartz M, Bailey J, Goodson J. Primary Care Practice Transformation in the Era of COVID-19 and Beyond: Key Principles for General Internal Medicine Practitioners. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2021. PMID: 34845581


  33. Cazabon D, Farrell M, Gupta R, Joseph L, Pathni AK, Sahoo S, Kunwar A, Elliott K, Cohn J, Frieden TR, Moran AE. A simple six-step guide to National-Scale Hypertension Control Program implementation. Journal of human hypertension 2021. PMID: 34702957


  34. Hoffer-Hawlik M, Moran A, Zerihun L, Usseglio J, Cohn J, Gupta R. Telemedicine interventions for hypertension management in low- and middle-income countries: A scoping review. PloS one 2021. PMID: 34242327


  35. Gupta R, Azhdam AM, Borrelli M. Schwannoma of the Supraglottis. Ear, nose, & throat journal 2021. PMID: 34112006


  36. Hoffer-Hawlik MA, Moran AE, Burka D, Kaur P, Cai J, Frieden TR, Gupta R. Leveraging Telemedicine for Chronic Disease Management in Low- and Middle-Income Countries During Covid-19. Global heart 2020. PMID: 33150128


  37. Kapoor B, Gulati M, Singh SK, Khatik GL, Gupta R, Kumar R, Kumar R, Gowthamarajan K, Mahajan S, Gupta S. Fail-safe nano-formulation of prodrug of sulfapyridine: Preparation and evaluation for treatment of rheumatoid arthritis. Materials science & engineering. C, Materials for biological applications 2020. PMID: 33254964


  39. Sardana P, Banker J, Gupta R, Kotdawala A, Lalitkumar PGL, Banker M. The Influence of Delayed Blastocyst Development on the Outcome of Frozen-Thawed Transfer of Euploid and Untested Embryos. Journal of human reproductive sciences 2020. PMID: 32792766


  41. Liu C, Miyajima T, Melangath G, Miyai T, Vasanth S, Deshpande N, Kumar V, Ong Tone S, Gupta R, Zhu S, Vojnovic D, Chen Y, Rogan EG, Mondal B, Zahid M, Jurkunas UV. Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected. Proceedings of the National Academy of Sciences of the United States of America 2019. PMID: 31852820


  42. Gupta R, Verma R, Pradhan D, Jain AK, Umamaheswari A, Rai CS. An in silico approach towards identification of novel drug targets in pathogenic species of Leptospira. PloS one 2019. PMID: 31430340


  44. Gupta H, Gupta R, Rai S, Kataria H, Jain V, Shankar V. Is empirical use of the antibiotic combination of cefuroxime and clavulanic acid rational? Journal of global antimicrobial resistance 2019. PMID: 30611930


  45. Lyson HC, Ackerman S, Lyles C, Schillinger D, Williams P, Gourley G, Gupta R, Handley M, Sarkar U. Redesigning primary care in the safety net: A qualitative analysis of team-based care implementation. Healthcare (Amsterdam, Netherlands) 2018. PMID: 30552044


  47. Dubé K, Gupta R, Kong M, Knox M, Bodenheimer T. Continuity of Care in Residency Teaching Practices: Lessons from "Bright Spots". The Permanente journal 2018. PMID: 30010534


  48. Dulay M, Laponis R, O'Brien BC, Gupta R, Ramanan RA, Julian K. An Intensive Continuity Clinic Immersion Experience for Interns: A Springboard to Confidence and Satisfaction With Continuity Clinic. Journal of graduate medical education 2017. PMID: 29075384


  50. Gupta R, Pradhan D, Jain AK, Rai CS. TiD: Standalone software for mining putative drug targets from bacterial proteome. Genomics 2016. PMID: 27856224


  51. Gupta R, Barnes K, Bodenheimer T. Clinic First: 6 Actions to Transform Ambulatory Residency Training. Journal of graduate medical education 2016. PMID: 27777657


  52. Gupta R, Dubé K, Bodenheimer T. The Road to Excellence for Primary Care Resident Teaching Clinics. Academic medicine : journal of the Association of American Medical Colleges 2016. PMID: 26826073


  53. Fontil V, Gupta R, Bibbins-Domingo K. Missed opportunities: young adults with hypertension and lifestyle counseling in clinical practice. Journal of general internal medicine 2015. PMID: 25761619


  54. Willard-Grace R, Dubé K, Hessler D, O'Brien B, Earnest G, Gupta R, Shunk R, Grumbach K. Panel management, team culture, and worklife experience. Families, systems & health : the journal of collaborative family healthcare 2015. PMID: 25730504


  55. Rogers EA, Hessler D, Dube K, Willard-Grace R, Gupta R, Bodenheimer T, Grumbach K. The panel management questionnaire: a tool to measure panel management capability. The Permanente journal 2015. PMID: 25785637


  56. Gupta R, Bodenheimer T. How primary care practices can improve continuity of care. JAMA internal medicine 2013. PMID: 24042733


  57. Gupta R, Davis E, Horton C. Interval examination: building primary care teams in an urban academic teaching clinic. Journal of general internal medicine 2013. PMID: 24043568


  58. Sarkar U, Handley MA, Gupta R, Tang A, Murphy E, Seligman HK, Shojania KG, Schillinger D. Use of an interactive, telephone-based self-management support program to identify adverse events among ambulatory diabetes patients. Volume 23 of Issue 4. Journal of general internal medicine 2008. PMID: 18373145


  60. Bangsberg DR, Acosta EP, Gupta R, Guzman D, Riley ED, Harrigan PR, Parkin N, Deeks SG. Adherence-resistance relationships for protease and non-nucleoside reverse transcriptase inhibitors explained by virological fitness. AIDS (London, England) 2006. PMID: 16511415


  61. Kushel MB, Gupta R, Gee L, Haas JS. Housing instability and food insecurity as barriers to health care among low-income Americans. Volume 21 of Issue 1. Journal of general internal medicine 2006. PMID: 16423128